This is an old topic that come up now and again. Here is a link to 2010 on the exact issue. RugerForum.com ? View topic - 44 mag loads w/Unique powder
I like Unique powder and the article talks about 10.7-11.5 grains in the reloading books. I have used the John Taffin load of 10.0 grains behind a 240 grain that I cast. It also works great with the Berry bullets I buy at Cabela's.
Ten grains of Unique is supposed to give 1,000 fps which equals to 533 foot pounds. In my 2.5 inch, 4 inch barrel, and Ruger 5.5 inch it is a ***** cat to shoot. Actually feels less to me than a standard 1911 in 45 acp. It is fine for hunting small game at reasonable ranges and plenty for any self defense issues.
By reference, the white box 240 grain factory ammo, PMC and Remington all go about 1,250 fps from my 4 inch which is about 833 foot pounds. So it is only about 65% of a full power load. Actually the premium ammo gets well over 1,000 foot pounds so it is only 50% of so of the really hot stuff.
If you drop back to the plinking or 44 special level loads say 8.5 grains of unique you lose a lot of velocity so you cannot really shoot at coyotes or game reliably because at those low speeds you drop like 18 inches at 100 yards. If you are just shooting paper or cans up close it would not matter.
If you reload I might also suggest you consider loading round ball loads. You can buy .433 round balls for muzzle loading rifles or mold them as I do. They weigh about 140 grains each and I load 2 of them for 280 grains in front of that 10.0 grains of unique. In my 2.5 inch barrel they spread vertically about 8 inches at 25 yards. Pretty fun for plinking because that spread increases your odds of hitting. They are great on 8 inch falling plates. People at the range often are surprised at how I seldom miss one. Sometimes I tell them I am shooting 2 balls, sometimes not. Enjoy.
I tried the lighter loads but if I am looking for zero recoil I just go to my Single Six. Just seems like a waste to shoot the wimpy loads in such a big gun. Except, they are great for kids who may be afraid of the noise and recoil. Enjoy.