Great details and interesting topic.
Am in the camp of if need a bigger gun, buy a bigger gun. Though did talk to Henry once about 45colt +p in my scout carbine, they said it was fine. No doubt many modern levers are strong guns. Yet if want more 45 lever power, I go with good old 4570.
Personally, am also more comfortable with reducing 454 loads in its beefed up case rather than stretching great 45 colt or any other case to its limits with +p.
In similiar fashion, I like to think of any of these cool guns being a reliable performer for a lifetime and beyond, while getting the most service out of it.