As I am curious kind of guy, I wanted to see the affect of seating the bullet to different depths but use the same bullet, powder, and primer. The forums are rampent with 'worry' over seating depth and careful OAL measurements .... Anyway ....
Here are the results for .45 Colt :
41.54mm OAL, 7.0g Red Dot, 255g SWC, CCI-300, 901fps, 30 SD, 125 ES, 15 shots
40.41mm OAL, 7.0g Red Dot, 255g SWC, CCI-300, 933fps, 12 SD, 38 ES, 15 shots
38.73mm OAL, 7.0g Red Dot, 255g SWC, CCI-300, 965fps, 11 SD, 44 ES, 15 shots
38.73mm OAL, 6.0g Red Dot, 255g SWC, CCI-300, 862fps, 13 SD, 32 ES, 15 shots
41.54mm is very bottom of crimp groove
40.41mm is very top of crimp groove
38.73mm is very top of the driving band
You can draw you own conclusions here .... but as you see in .45 Colt the seating depth isn't going to blow up your revolver if you just crimp somewhere in the crimp groove
. Also, the deeper you seat the bullet the better your consistency.
Here is an article that is similar to this line of testing : Thoughts on Improving Revolver Loads