I shoot a RCBS 255 452 water quenched wheel weight that drops about that weight, and have used H110 @ 23-24 grains to push it out the barrel of my NMBH.
A little word of caution make sure you use a MAGNUM LP primer to light it up, I had some load data that did not state the use of LPM primers. Glad I only loaded 10, 'cause I had a SQUIB on the first drop of the hammer.
Check out John Linebaughs web site and read his stuff on the heavy loadings for .45Colt it is
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